The use of cannabis for medicinal purposes dates back thousands of years with the earliest known descriptions appearing in the ancient writings and folklore of India and China. (Abel EL).
All mammals – including humans — produce cannabinoids (the active molecules in cannabis) internally. Both these naturally produced internal canabinoids (endo canabinoids) and plant-based cannabinoids bind to known cannabis receptors CB1 and CB2, activating intercellular signal pathways, with the potential for therapeutically beneficial effects.
There are strong indications that medical cannabis has a unique role to play treating a wide variety of conditions including chronic pain, inflammatory diseases, symptoms associated with cancer, mood disorders, PTSD, epilepsy, intractable seizures, spasticity associated with multiple sclerosis and many others. In many patients, cannabis-based treatments promise reduced side effects, and benefits such as improved mood and appetite.
Currently, scientist are working to confirm the existence of other cannabinoid receptors. Researchers continue to study the therapeutic potential of over 80 medically significant cannabis compounds. This work is expected to yield a wide variety of new treatments in the future, targeting diverse health challenges from Attention Deficit Hyperactivity Disorder (ADHD) to obesity.